SCHEMBL13347367

SCHEMBL13347367

C=CCC(CC=C)CC(C(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.47
GRIK2 Q13002 2/20 0.47
CYP2C19 P33261 1/20 0.41
CPA1 P15085 1/20 0.41
ABCC4 O15439 1/20 0.38
MAPT P10636 1/20 0.38
ENPEP Q07075 1/20 0.34
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31636 0.78 GRIK1 (0.48) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL4021287 0.78 CPA1 (0.44) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL9709901 0.78 SLC1A2 (0.38) GRIK1GRIK2CYP2C19CPA1
SCHEMBL19899237 0.78 CYP2C19 (0.49) CYP2C19CPA1
SCHEMBL19899203 0.78 CYP2C19 (0.49) CYP2C19CPA1
SCHEMBL19899202 0.78 CYP2C19 (0.49) CYP2C19CPA1
SCHEMBL7600448 0.76 GRIK1 (0.48) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL28385153 0.76 TSHR (0.38) GRIK1GRIK2MAPT
Potassium SCHEMBL31299609 0.76 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL31299617 0.76 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140155640-A1 Surface Functionalised Nanoparticles NANOCO TECHNOLOGIES LTD. (GB) 2014-06-05 US disclosed
US-8394976-B2 Surface functionalised nanoparticles Nanoco Technologies, Ltd. (GB) 2013-03-12 US disclosed
US-8394976-B2 Surface functionalised nanoparticles Nanoco Technologies, Ltd. (GB) 2013-03-12 US disclosed
US-20100113813-A1 SURFACE FUNCTIONALISED NANOPARTICLES NANOCO TECHNOLOGIES LIMITED (GB) 2010-05-06 US disclosed
US-20100113813-A1 SURFACE FUNCTIONALISED NANOPARTICLES NANOCO TECHNOLOGIES LIMITED (GB) 2010-05-06 US disclosed
US-20100068522-A1 Surface Functionalised Nanoparticles NANOCO TECHNOLOGIES LIMITED (GB) 2010-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140155640-A1 Surface Functionalised Nanoparticles EPCAM, L1CAM, CD4 GRIK1 3904/4885GRIK2 4179/4885CYP2C19 2707/4885
US-20100113813-A1 SURFACE FUNCTIONALISED NANOPARTICLES CD47, CD63, EPCAM GRIK1 4591/4885GRIK2 4513/4885CYP2C19 3233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.