SCHEMBL28385153

SCHEMBL28385153

C=CCOC(=O)C(CC(CC=C)CC=C)C(=O)OCC=C

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
MAPT P10636 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19105301 0.83 TSHR (0.42) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL20954020 0.79 TSHR (0.40) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL13347367 0.76 GRIK1 (0.47) MAPTGRIK1GRIK2
SCHEMBL4766772 0.76 TSHR (0.42) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL7975200 0.74 TSHR (0.41) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL28431074 0.74 TSHR (0.37) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL8164447 0.74 TSHR (0.42) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL28662748 0.73 TSHR (0.47) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL32679948 0.73 TSHR (0.43) TSHRMAPTCACNA1BAPBA1CYP3A4
SCHEMBL770455 0.72 TSHR (0.41) TSHRMAPTCACNA1BAPBA1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107078352-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2020-04-28 CN disclosed