Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18723000 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL15478669 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8740048 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7106617 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL23855449 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3689336 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL25340521 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3088610 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL20943325 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4379473 | 1.00 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8753686-B2 | Surface-treating agents, surface-treated powders, and cosmetics comprising the same | SHISEIDO CO., LTD. (JP) | 2014-06-17 | — | — | US | disclosed |
| US-20110280946-A1 | Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same | SHISEIDO CO., LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| EP-2112179-B1 | Surface-treated powders, and cosmetics comprising the same | SHISEIDO CO LTD (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-20100119470-A1 | Method Of Reducing The Appearance Of Wrinkles | SHISEIDO COMPANY, LTD. (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-1803750-B1 | USE OF A POLYMER FOR SURFACE-TREATING A POWDER | SHISEIDO CO LTD (JP) | 2009-12-09 | — | — | EP | disclosed |
| EP-2112179-A1 | Surface-treated powders, and cosmetics comprising the same | Shiseido Co., Ltd. (JP) | 2009-10-28 | — | — | EP | disclosed |
| US-20080081029-A1 | acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability | SHISEIDO CO., LTD. (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1803750-A1 | SURFACE-TREATING AGENT, SURFACE-TREATED POWDER, AND COSMETIC PREPARATION CONTAINING SAME | Shiseido Company, Limited (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20070148120-A1 | Skin preparations for external use for wrinkle reduction | SHISEIDO COMPANY LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1704849-A1 | SKIN PREPARATIONS FOR EXTERNAL USE FOR WRINKLE DIMINUTION | SHISEIDO COMPANY, LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |
| CN-1711082-A | Novel hydroxyindoles, their use as phosphodiesterase 4 inhibitors and process for their preparation | ELBION AG (DE) | 2005-12-21 | — | — | CN | disclosed |
| EP-0389269-B1 | DIESTERS AND THEIR USE IN WAXES | UNICHEMA CHEMIE B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |
| US-5104586-A | Having branched saturated hydrocarbon chains; for cosmetic emulsions | UNILEVER PATENT HOLDINGS B.V. (NL) | 1992-04-14 | — | — | US | disclosed |
| EP-0389269-A1 | Diesters and their use in waxes | UNICHEMA CHEMIE B.V. (NL) | 1990-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081029-A1 | acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability | CHRM1, H1-0, H1-2 | LMNA 2921/4885ALDH1A1 142/4885HSD17B10 1723/4885 |
| US-20110280946-A1 | Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same | CHRM1, H1-0, H1-2 | LMNA 1417/4885ALDH1A1 115/4885HSD17B10 2655/4885 |
| US-20070148120-A1 | Skin preparations for external use for wrinkle reduction | CUTA, MMS19, COL14A1 | LMNA 167/4885ALDH1A1 4533/4885HSD17B10 3120/4885 |
| US-20100119470-A1 | Method Of Reducing The Appearance Of Wrinkles | CUTA, MMS19, COL14A1 | LMNA 112/4885ALDH1A1 4489/4885HSD17B10 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.