Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701931 | 0.81 | CYP2C19 (0.55) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL14880510 | 0.78 | CYP2C19 (0.51) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL277284 | 0.77 | CYP2C19 (0.86) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL19033845 | 0.76 | CYP2C19 (0.68) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| Hydrochloric Acid SCHEMBL9679507 | 0.76 | CYP2C19 (0.83) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL1601462 | 0.75 | CYP2C19 (0.48) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL6979196 | 0.73 | CYP2C19 (0.68) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL6979199 | 0.73 | CYP2C19 (0.72) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL1812268 | 0.71 | CYP2C9 (0.70) | CYP2C19CYP2C9ALDH1A1MAPTCA12 | |
| SCHEMBL158686 | 0.71 | CYP2C19 (0.70) | CYP2C19CYP2C9MAPTSMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | SDHA, SDHB, UROD | CYP2C19 6/4885CYP2C9 19/4885ALDH1A1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.