Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320262 | 1.00 | RAPGEF4 (0.74) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL22814342 | 0.91 | RAPGEF4 (0.63) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1921160 | 0.91 | RAPGEF4 (0.63) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7866844 | 0.91 | RAPGEF4 (0.63) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30575353 | 0.89 | RAPGEF4 (0.61) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8598906 | 0.89 | RAPGEF4 (0.61) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29445703 | 0.87 | RAPGEF4 (0.65) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1921159 | 0.87 | RAPGEF4 (0.65) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL21776018 | 0.87 | RAPGEF4 (0.59) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7003942 | 0.87 | RAPGEF4 (0.64) | RAPGEF4MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11261403-B2 | Stabilized compositions comprising leuco compounds | MILLIKEN & COMPANY (US) | 2022-03-01 | — | — | US | claimed |
| US-11136535-B2 | Leuco colorants as bluing agents in laundry care compositions | THE PROCTER & GAMBLE COMPANY (US) | 2021-10-05 | — | — | US | claimed |
| EP-3830232-A1 | LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS | The Procter & Gamble Company (US) | 2021-06-09 | — | — | EP | claimed |
| WO-2020023812-A1 | LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2020-01-30 | — | — | WO | claimed |
| US-20200032167-A1 | STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS | MILLIKEN & COMPANY | 2020-01-30 | — | — | US | claimed |
| US-20200032173-A1 | LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY | 2020-01-30 | — | — | US | claimed |
| US-12127473-B2 | Di-, tri- and tetraphenylindane derivates and their use in organic electronics | DOTTIKON ES HOLDING AG (CH) | 2024-10-22 | — | — | US | disclosed |
| US-12091553-B2 | Core-shell dye, near-infrared absorbing composition including the same, and near-infrared absorbing film | SAMSUNG SDI CO., LTD. (KR) | 2024-09-17 | — | — | US | disclosed |
| EP-4365180-A1 | RARE EARTH COMPLEX | Tosoh Corporation (JP) | 2024-05-08 | — | — | EP | disclosed |
| US-11944010-B2 | Organic electroluminescent device | KYULUX, INC. (JP) | 2024-03-26 | — | — | US | disclosed |
| US-20230392018-A1 | COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS | MILLIKEN & COMPANY | 2023-12-07 | — | — | US | disclosed |
| US-20230348724-A1 | CORE-SHELL DYE, NEAR-INFRARED ABSORBING COMPOSITION INCLUDING THE SAME, AND NEAR-INFRARED ABSORBING FILM | SAMSUNG SDI CO., LTD. (KR) | 2023-11-02 | — | — | US | disclosed |
| WO-2023190472-A1 | CYCLOHEXYLENEDIAMINIUM SALT, USE THEREOF, AND MSE TYPE ZEOLITE OBTAINED USING SAME | 公益財団法人相模中央化学研究所 | 2023-10-05 | — | — | WO | disclosed |
| WO-2004011692-A2 | PROCESS FOR PREPARING DIHYDROCARBYLAMINO METAL COMPOUNDS | ALBEMARLE CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |
| US-20020048710-A1 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2002-04-25 | — | — | US | disclosed |
| US-4558101-A | FROM HYDROCARBON POLYMER CONTAINING OLEFINIC GROUPS WITH HYDROGEN CARBON MONOXIDE AND AMINE USING GROUP 8 METAL CATALYST | W. R. GRACE & CO. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4526936-A | Reacting polymeric hydrocarbon, primary or secondary amine, carbon monoxide, hydrogen, in the presence of group VIII metal catalyst | W. R. GRACE & CO. (US) | 1985-07-02 | — | — | US | disclosed |
| US-4375560-A | Process for the preparation of 3,5-dimethylaniline (sym. m-xylidine) | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-01 | — | — | US | disclosed |
| US-4375561-A | Process for the preparation of aromatic amines | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-01 | — | — | US | disclosed |
| US-4312965-A | Process for forming amine/amide containing polymers | W. R. GRACE & CO. (US) | 1982-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12127473-B2 | Di-, tri- and tetraphenylindane derivates and their use in organic electronics | NR0B2, KCNJ2, TRRAP | RAPGEF4 2355/4885MEN1 2154/4885KMT2A 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.