Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320262 | 0.87 | RAPGEF4 (0.74) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL1334869 | 0.87 | RAPGEF4 (0.74) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL1335872 | 0.84 | KMT2A (0.44) | RAPGEF4KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL22814342 | 0.78 | RAPGEF4 (0.63) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL7866844 | 0.78 | RAPGEF4 (0.63) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL1921160 | 0.78 | RAPGEF4 (0.63) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL8598906 | 0.77 | RAPGEF4 (0.61) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL30575353 | 0.77 | RAPGEF4 (0.61) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL13776396 | 0.77 | RAPGEF4 (0.73) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL1921159 | 0.76 | RAPGEF4 (0.65) | RAPGEF4KMT2AMEN1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613752-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | Samsung Electronics Co., Ltd. (KR) | 2020-02-26 | — | — | EP | disclosed |