Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12284426 | 0.89 | ALOX5 (0.48) | ALOX5MAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL12177033 | 0.85 | ALOX5 (0.53) | ALOX5MAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL12284366 | 0.82 | ALOX5 (0.41) | ALOX5MAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL12284429 | 0.80 | ALOX5 (0.40) | ALOX5MAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL11561024 | 0.79 | ALDH1A1 (0.55) | ALOX5MAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL11562896 | 0.76 | ALDH1A1 (0.58) | ALOX5MAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL12285979 | 0.73 | ALOX5 (0.55) | ALOX5MAPTALDH1A1KDM4EPTGS2 | |
| SCHEMBL10801295 | 0.69 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EPTGS2LMNA | |
| SCHEMBL12286391 | 0.69 | PPARD (0.39) | MAPTALDH1A1KDM4EPTGS2LMNA | |
| SCHEMBL10449749 | 0.69 | PTGDR2 (0.47) | ALOX5MAPTALDH1A1KDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050577-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |