Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177033 | 0.94 | ALOX5 (0.53) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL11562896 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL12284426 | 0.80 | ALOX5 (0.48) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL10801295 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL13352180 | 0.79 | ALOX5 (0.47) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL11288829 | 0.79 | MAPT (0.52) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL11292797 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL11563601 | 0.75 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL11455410 | 0.75 | PTGS2 (0.66) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL9451885 | 0.75 | MAPT (0.49) | ALDH1A1MAPTKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168315-A | ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1979-09-18 | — | — | US | claimed |
| US-4168315-A | ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1979-09-18 | — | — | US | disclosed |