Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320698 | 0.82 | TRPM2 (0.55) | HDAC3MMP1MMP2MMP9EGFR | |
| SCHEMBL16215236 | 0.78 | KDM4E (0.48) | HDAC3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL14289948 | 0.74 | MMP1 (0.56) | MMP1MMP2MMP9NPC1LMNA | |
| SCHEMBL14242079 | 0.71 | MMP1 (0.71) | MMP1MMP2MMP9EGFR | |
| SCHEMBL12723530 | 0.71 | MMP1 (0.65) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL12723528 | 0.71 | MMP1 (0.65) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL5756784 | 0.71 | KDM4E (0.58) | HDAC3HDAC1HDAC2RAB9ANPC1 | |
| SCHEMBL5756780 | 0.71 | KDM4E (0.58) | HDAC3HDAC1HDAC2RAB9ANPC1 | |
| SCHEMBL14021284 | 0.70 | NPC1 (0.69) | HDAC3HDAC1HDAC2MMP1MMP2 | |
| SCHEMBL13352230 | 0.69 | MMP1 (0.64) | HDAC3HDAC1HDAC2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130497-A1 | Therapeutic Compounds | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130497-A1 | Therapeutic Compounds | NFATC1, NAT1, AADAC | HDAC3 51/4885HDAC1 60/4885HDAC2 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.