Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 8/20 | 0.56 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.56 |
| ▸ | SPIN1 | Q9Y657 | 5/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028142 | 0.86 | EHMT2 (0.67) | EHMT2EHMT1SPIN1HTR4MEN1 | |
| SCHEMBL13355146 | 0.83 | EHMT2 (0.47) | EHMT2EHMT1SPIN1ACHE | |
| SCHEMBL4379114 | 0.79 | HTR4 (0.60) | EHMT2EHMT1SPIN1HTR4MEN1 | |
| SCHEMBL19260705 | 0.78 | HTR4 (0.56) | EHMT2EHMT1SPIN1HTR4MEN1 | |
| SCHEMBL2926517 | 0.78 | HTR4 (0.56) | EHMT2EHMT1SPIN1HTR4MEN1 | |
| SCHEMBL19607184 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP3A4 | |
| SCHEMBL13662484 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP3A4 | |
| SCHEMBL30462820 | 0.78 | ACHE (0.65) | ACHE | |
| SCHEMBL29038401 | 0.78 | ACHE (0.65) | ACHE | |
| SCHEMBL20028123 | 0.78 | EHMT2 (0.58) | EHMT2EHMT1SPIN1HTR4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709640-B2 | Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-05-04 | — | — | US | disclosed |