Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897312 | 0.74 | ALDH1A1 (0.58) | KMT2AALDH1A1 | |
| SCHEMBL13355237 | 0.71 | PLA2G1B (0.45) | KDM4EKMT2AALDH1A1HPGDNAMPT | |
| SCHEMBL29123175 | 0.71 | KDM4E (0.82) | KDM4EKMT2AMLYCDHSD17B10TSHR | |
| SCHEMBL14297349 | 0.70 | PKM (0.61) | KMT2AUSP2ALDH1A1HPGD | |
| SCHEMBL4818087 | 0.68 | CRBN (0.56) | CYP2D6CYP2C9TSHRCYP2C19ALDH1A1 | |
| SCHEMBL4818101 | 0.68 | CRBN (0.56) | CYP2D6CYP2C9TSHRCYP2C19ALDH1A1 | |
| SCHEMBL4815807 | 0.67 | MAPK1 (0.57) | KMT2ACYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL4815797 | 0.67 | MAPK1 (0.57) | KMT2ACYP2C9CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL19159945 | 0.67 | CYP3A4 (0.68) | KMT2ACYP2D6CYP2C9HSD17B10TSHR | |
| SCHEMBL10801846 | 0.67 | KDM4E (1.00) | KDM4EKMT2AMLYCDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787982-B1 | 11Beta-Hydroxysteroid dehydrogenase type 1 active compounds | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-05-12 | — | — | EP | disclosed |