Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559446 | 0.79 | CASP3 (0.38) | HTR2CHTR2BHTR2AKEAP1 | |
| SCHEMBL3559442 | 0.79 | CASP3 (0.38) | HTR2CHTR2BHTR2AKEAP1 | |
| SCHEMBL3559448 | 0.79 | CASP3 (0.38) | HTR2CHTR2BHTR2AKEAP1 | |
| SCHEMBL19541909 | 0.66 | MAOA (0.44) | — | |
| SCHEMBL13355697 | 0.65 | PDK4 (0.41) | — | |
| SCHEMBL17270371 | 0.65 | CASP3 (0.38) | HTR2CHTR2BHTR2AKEAP1 | |
| SCHEMBL13315691 | 0.65 | CASP3 (0.38) | HTR2CHTR2BHTR2AKEAP1 | |
| SCHEMBL27659465 | 0.65 | CASP3 (0.38) | HTR2CHTR2BHTR2AKEAP1 | |
| SCHEMBL10044107 | 0.65 | HTR2B (0.48) | HTR2CHTR2BHTR2A | |
| SCHEMBL14315974 | 0.64 | MAOA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056633-A2 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-20 | — | — | WO | disclosed |