Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 7/20 | 0.41 |
| ▸ | RAF1 | P04049 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240510 | 0.83 | KDR (0.45) | MAPTKDRHCAR3MEN1ALDH1A1 | |
| SCHEMBL3242738 | 0.83 | KDM4E (0.54) | MAPTTP53KDRMEN1ALDH1A1 | |
| SCHEMBL3247925 | 0.81 | KDR (0.42) | HDAC6MAPTKDRMEN1RAB9A | |
| SCHEMBL3246021 | 0.81 | TDP2 (0.44) | TSHRKDRGSK3BHCAR3NSD2 | |
| SCHEMBL3242077 | 0.81 | CTSC (0.47) | SYKCYP3A4 | |
| SCHEMBL3262625 | 0.79 | RHOA (0.51) | MAPTTP53BRAFABCG2MEN1 | |
| SCHEMBL3262264 | 0.78 | TRIM24 (0.41) | MAPTKDRPLK1MEN1APAF1 | |
| SCHEMBL3238724 | 0.77 | MEN1 (0.43) | MAPTTP53BRAFMEN1ALDH1A1 | |
| SCHEMBL13356400 | 0.76 | MEN1 (0.40) | MAPTTP53SYKMEN1RAB9A | |
| SCHEMBL3247960 | 0.75 | KMT2A (0.51) | MAPTKDRMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |