Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264084 | 0.82 | GAA (0.38) | KDRPLK1MEN1KMT2AGAA | |
| SCHEMBL13356451 | 0.78 | HDAC6 (0.49) | KDRPLK1MEN1KMT2AGAA | |
| SCHEMBL3261356 | 0.78 | CDK8 (0.44) | TRIM24TRIM33GAAPOLBERN1 | |
| SCHEMBL3246021 | 0.76 | TDP2 (0.44) | XDHKDRGAATDP2NSD2 | |
| SCHEMBL3247925 | 0.74 | KDR (0.42) | KDRMEN1KMT2AMAPT | |
| SCHEMBL3247960 | 0.73 | KMT2A (0.51) | KDRMEN1KMT2AMAPTPOLB | |
| SCHEMBL10984047 | 0.72 | TRIM24 (0.59) | TRIM24TRIM33MEN1KMT2AGAA | |
| SCHEMBL3242098 | 0.72 | PDE10A (0.45) | XDH | |
| SCHEMBL3262625 | 0.72 | RHOA (0.51) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL3242738 | 0.72 | KDM4E (0.54) | KDRMEN1KMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |