Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335613 | 0.83 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL1225526 | 0.81 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1MERTKKDM4E | |
| SCHEMBL1337889 | 0.79 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL28215127 | 0.78 | TDP1 (0.56) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL16621590 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL1336754 | 0.75 | TDO2 (0.45) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL12130375 | 0.75 | GRIN2D (0.44) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL24476816 | 0.74 | TDO2 (0.39) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL1134024 | 0.74 | CYP19A1 (0.40) | ALDH1A1POLBMAPTAMY1A | |
| SCHEMBL1337810 | 0.74 | MEN1 (0.65) | MEN1KMT2AALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | TUBA1C, TUBB1, TUBB3 | MEN1 2570/4885KMT2A 1581/4885ALDH1A1 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.