SCHEMBL13358577

SCHEMBL13358577

CC1(C)c2cc(/C=C/c3ccc(N(c4ccccc4)c4ccccc4)cc3)ccc2-c2ccc(N(c3ccc4c5c(cccc35)-c3ccccc3-4)c3cc4ccccc4c4ccccc34)cc21

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
APP P05067 1/20 0.31
PDK2 Q15119 1/20 0.31
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
CTNNB1 P35222 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13358473 0.95 ALDH1A1 (0.36) ALDH1A1MAPK1L3MBTL1HPGDTSHR
SCHEMBL13358261 0.92 APP (0.36) ALDH1A1MAPK1L3MBTL1APPPDK2
SCHEMBL13358571 0.91 APP (0.33) ALDH1A1MAPK1L3MBTL1APPPDK2
SCHEMBL13358296 0.91 APP (0.33) ALDH1A1MAPK1L3MBTL1APPPDK2
SCHEMBL13358226 0.91 APP (0.37) ALDH1A1MAPK1L3MBTL1APPPDK2
SCHEMBL13358578 0.91 APP (0.37) ALDH1A1MAPK1L3MBTL1APPPDK2
SCHEMBL13371953 0.91 APP (0.34) ALDH1A1MAPK1L3MBTL1APPPDK2
SCHEMBL13358188 0.90 RELA (0.35) ALDH1A1MAPK1L3MBTL1APPPDK2
SCHEMBL13358295 0.90 APP (0.32) ALDH1A1MAPK1L3MBTL1APPMEN1
SCHEMBL13358586 0.90 PDK2 (0.37) ALDH1A1MAPK1L3MBTL1APPPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010058995-A1 ELECTROLUMINESCENT DEVICE USING THE ELECTROLUMINESCENT COMPOUNDS GRACEL DISPLAY INC. (KR) 2010-05-27 WO disclosed
EP-2189508-A2 Electroluminescent device using electroluminescent compounds Gracel Display Inc. (KR) 2010-05-26 EP disclosed