Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686607 | 0.83 | KMT2A (0.49) | HPGDCYP1A2CYP2C9CYP2C19KCNMA1 | |
| SCHEMBL1092461 | 0.81 | RAB9A (0.58) | HPGDCYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL29373841 | 0.78 | RAB9A (0.57) | HPGDCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL8686668 | 0.78 | HPGD (0.50) | HPGDCYP1A2CYP2C9CYP2C19KIF11 | |
| SCHEMBL5218510 | 0.78 | PDK1 (0.56) | HPGDCYP1A2CYP2C9CYP2C19KIF11 | |
| SCHEMBL1426650 | 0.78 | RAB9A (0.57) | HPGDCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL31226789 | 0.77 | MEN1 (0.67) | HPGDKMT2AMEN1GAARAB9A | |
| SCHEMBL5527378 | 0.77 | MEN1 (0.67) | HPGDKMT2AMEN1GAARAB9A | |
| SCHEMBL6836389 | 0.76 | CXCR2 (0.63) | HPGDCYP1A2CYP2C9CYP2C19KIF11 | |
| SCHEMBL5534456 | 0.75 | KMT2A (0.66) | HPGDKMT2AMEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293919-B2 | Antibacterial sulfone and sulfoxide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-10-23 | — | — | US | disclosed |