Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359018 | 0.83 | HPGD (0.50) | KMT2AHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL90967 | 0.80 | ALDH1A1 (0.59) | KMT2ATDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL1224549 | 0.78 | KCNMA1 (0.62) | KMT2AALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL27606751 | 0.78 | NEU3 (0.53) | KMT2AHPGDHSD17B10ALDH1A1NPC1 | |
| SCHEMBL16588403 | 0.78 | TDP1 (0.50) | KMT2ATDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10896720 | 0.77 | ALDH1A1 (0.60) | KMT2ATDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10034515 | 0.77 | LMNA (0.56) | KMT2ATDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL4913081 | 0.77 | RXFP1 (0.51) | KMT2ATDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL30707863 | 0.77 | ALDH1A1 (0.60) | KMT2ATDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL11207191 | 0.77 | HDAC1 (0.60) | KMT2ATDP1HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |