SCHEMBL13359040

SCHEMBL13359040

C=C(O)C(C)(C)Oc1ccc(C(=O)/C=C/c2ccc(O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.63
▸ F3 P13726 4/20 0.63
▸ RAB9A P51151 4/20 0.63
▸ KMT2A Q03164 4/20 0.63
▸ MEN1 O00255 3/20 0.63
▸ P4HB P07237 2/20 0.63
▸ ALDH1A1 P00352 2/20 0.63
▸ CALM1 P0DP23 1/20 0.63
▸ XDH P47989 1/20 0.63
▸ ABCG2 Q9UNQ0 4/20 0.59
▸ MAOB P27338 4/20 0.59
▸ BCHE P06276 1/20 0.56
▸ MAOA P21397 2/20 0.56
▸ POLB P06746 1/20 0.56
▸ CYP3A4 P08684 2/20 0.55
▸ HSPD1 P10809 2/20 0.55
▸ HSPE1 P61604 2/20 0.55
▸ CYP1B1 Q16678 2/20 0.55
▸ PKM P14618 1/20 0.55
▸ NFKB1 P19838 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14491050 0.90 MAPT (0.66) MAPTF3RAB9AKMT2AMEN1
SCHEMBL25205883 0.90 MAPT (0.66) MAPTF3RAB9AKMT2AMEN1
SCHEMBL814358 0.90 MAPT (0.66) MAPTF3RAB9AKMT2AMEN1
SCHEMBL14491087 0.84 PPARG (0.52) —
SCHEMBL25237641 0.80 F3 (0.68) MAPTF3RAB9AKMT2AMEN1
SCHEMBL25212966 0.80 F3 (0.68) MAPTF3RAB9AKMT2AMEN1
SCHEMBL25216348 0.80 F3 (0.68) MAPTF3RAB9AKMT2AMEN1
SCHEMBL14491076 0.79 MAOB (0.66) MAPTF3RAB9AKMT2AMEN1
SCHEMBL14523081 0.79 MAOB (0.66) MAPTF3RAB9AKMT2AMEN1
SCHEMBL11533106 0.79 PPARG (0.69) MAPTF3RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
EP-1644312-B1 PREPARATION OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES GENFIT (FR) 2010-05-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885F3 5/4885RAB9A 480/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885F3 11/4885RAB9A 1327/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885F3 11/4885RAB9A 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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