SCHEMBL13359353

SCHEMBL13359353

OCCN1C=C/C(=C\C=C\c2sc3ccccc3[n+]2CCO)c2ccc(Br)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.41
PRMT5 O14744 1/20 0.41
CARM1 Q86X55 1/20 0.41
NPC1 O15118 5/20 0.37
RAB9A P51151 5/20 0.37
USP2 O75604 2/20 0.37
MTOR P42345 1/20 0.37
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
HTT P42858 4/20 0.36
BLM P54132 3/20 0.36
APP P05067 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
APAF1 O14727 1/20 0.35
ITGB2 P05107 1/20 0.35
ALPL P05186 1/20 0.35
ITGAM P11215 1/20 0.35
GFER P55789 1/20 0.35
MAPT P10636 3/20 0.33
THRB P10828 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26845450 0.96 PRMT1 (0.39) PRMT1PRMT5CARM1NPC1RAB9A
SCHEMBL26845465 0.92 PRMT1 (0.36) PRMT1PRMT5CARM1NPC1RAB9A
SCHEMBL26845336 0.91 INSR (0.40) PRMT1PRMT5CARM1NPC1RAB9A
SCHEMBL26845348 0.90 RAB9A (0.38) PRMT1PRMT5CARM1NPC1RAB9A
SCHEMBL26845426 0.89 PRMT1 (0.44) PRMT1PRMT5CARM1
SCHEMBL13108258 0.89 NPC1 (0.43) NPC1RAB9AUSP2MTORKMT2A
SCHEMBL26845406 0.87 PRMT1 (0.42) PRMT1PRMT5CARM1NPC1RAB9A
SCHEMBL26845388 0.85 PRMT1 (0.40) PRMT1PRMT5CARM1
SCHEMBL26845416 0.85 NPC1 (0.40) NPC1RAB9AUSP2MTORKMT2A
SCHEMBL26845305 0.85 PRMT1 (0.41) PRMT1PRMT5CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940499-B2 Reagent for blood analysis and method of use thereof SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2015-01-27 US disclosed
US-7709653-B2 Asymmetric cyanine compounds, their preparation methods and their uses SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO. LTD. (CN) 2010-05-04 US disclosed
US-20090305285-A1 ASYMMETRIC CYANINE COMPOUNDS, THEIR PREPARATION METHODS AND THEIR USES SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305285-A1 ASYMMETRIC CYANINE COMPOUNDS, THEIR PREPARATION METHODS AND THEIR USES IK, RCN1, RCC1 PRMT1 83/4885PRMT5 135/4885CARM1 193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.