Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691605 | 0.87 | USP2 (0.46) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL16614310 | 0.87 | USP2 (0.46) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL13359529 | 0.87 | USP2 (0.46) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL19270187 | 0.78 | CHRNB2 (0.46) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL10837418 | 0.77 | USP2 (0.38) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL10315910 | 0.74 | ALDH1A1 (0.63) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL19269485 | 0.74 | CHRNB2 (0.43) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL10167942 | 0.74 | — | — | |
| SCHEMBL11836421 | 0.73 | CHRNB2 (0.45) | USP2ALDH1A1ALOX15TDP1CHRNB2 | |
| SCHEMBL16614383 | 0.73 | CHRNB2 (0.45) | USP2ALDH1A1ALOX15TDP1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506908-B2 | From bicyclo(3.1.0)hexabe; decyclization; decarboxylation | MERCK & CO., INC. | 2003-01-14 | — | — | US | disclosed |
| US-20020016492-A1 | Process for preparing 3-hydroxymethyl-4-(aryl or heterocyclic)-cyclopentanones | MERCK SHARP & DOHME CORP. | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016492-A1 | Process for preparing 3-hydroxymethyl-4-(aryl or heterocyclic)-cyclopentanones | CCR1, CCR5, CCR6 | USP2 3542/4885ALDH1A1 2952/4885ALOX15 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.