Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.52 |
| ▸ | DTYMK | P23919 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14389876 | 1.00 | POLB (0.61) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL13326140 | 0.99 | POLB (0.60) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL14389942 | 0.99 | POLB (0.60) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL22434625 | 0.94 | POLB (0.62) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL14389999 | 0.93 | F2 (0.54) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL13326121 | 0.93 | F2 (0.54) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL14389990 | 0.93 | F2 (0.54) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL14389939 | 0.93 | F2 (0.54) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL13326155 | 0.93 | F2 (0.54) | POLBENPP1P2RY1F2P2RY2 | |
| SCHEMBL13326124 | 0.93 | F2 (0.54) | POLBENPP1P2RY1F2P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709449-B2 | Nucleic acid-based compounds and methods of use thereof | MIGENIX, INC. (CA) | 2010-05-04 | — | — | US | disclosed |