SCHEMBL14389876

SCHEMBL14389876

Nc1nc2c(ncn2[C@H]2C[C@@H](O)[C@@H](COP(=O)(S)O[C@@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3CO)O2)c(=O)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.61
▸ ENPP1 P22413 3/20 0.56
▸ P2RY1 P47900 1/20 0.56
▸ F2 P00734 1/20 0.54
▸ P2RY2 P41231 1/20 0.53
▸ P2RY4 P51582 1/20 0.53
▸ P2RY6 Q15077 1/20 0.53
▸ TERT O14746 1/20 0.52
▸ DTYMK P23919 2/20 0.51
▸ NT5E P21589 1/20 0.48
▸ STING1 Q86WV6 7/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13359725 1.00 POLB (0.61) POLBENPP1P2RY1F2P2RY2
SCHEMBL13326140 0.99 POLB (0.60) POLBENPP1P2RY1F2P2RY2
SCHEMBL14389942 0.99 POLB (0.60) POLBENPP1P2RY1F2P2RY2
SCHEMBL22434625 0.94 POLB (0.62) POLBENPP1P2RY1F2P2RY2
SCHEMBL14389999 0.93 F2 (0.54) POLBENPP1P2RY1F2P2RY2
SCHEMBL13326121 0.93 F2 (0.54) POLBENPP1P2RY1F2P2RY2
SCHEMBL14389990 0.93 F2 (0.54) POLBENPP1P2RY1F2P2RY2
SCHEMBL14389939 0.93 F2 (0.54) POLBENPP1P2RY1F2P2RY2
SCHEMBL13326155 0.93 F2 (0.54) POLBENPP1P2RY1F2P2RY2
SCHEMBL13326124 0.93 F2 (0.54) POLBENPP1P2RY1F2P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070270359-A1 Nucleic Acid-Based Compounds and Methods of Use Thereof IYER RADHAKRISHNAN P 2007-11-22 — — US disclosed
US-7256179-B2 Nucleic acid-based compounds and methods of use thereof MIGENIX, INC. (CA) 2007-08-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270359-A1 Nucleic Acid-Based Compounds and Methods of Use Thereof NT5C3B, HAVCR2, NSUN2 POLB 8/4885ENPP1 344/4885P2RY1 1157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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