SCHEMBL8614074

SCHEMBL8614074

Nc1ccn([C@H]2C[C@H](OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3O)[C@@H](CO)O2)c(=O)n1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 4/20 0.62
▸ P2RY4 P51582 4/20 0.62
▸ P2RY6 Q15077 3/20 0.62
▸ POLB P06746 3/20 0.62
▸ F2 P00734 2/20 0.56
▸ FUT5 Q11128 1/20 0.52
▸ TGM2 P21980 1/20 0.47
▸ NT5E P21589 2/20 0.46
▸ TERT O14746 1/20 0.45
▸ KRAS P01116 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8613676 1.00 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29365163 0.99 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29551697 0.99 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29424735 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2
SCHEMBL4078522 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29365434 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29702417 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29371610 0.95 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2
SCHEMBL31276800 0.94 P2RY2 (0.56) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29567368 0.94 P2RY2 (0.56) P2RY2P2RY4P2RY6POLBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240384261-A1 METHODS, COMPOSITIONS, AND KITS FOR PREPARING SEQUENCING LIBRARY GENEFIRST LIMITED (GB) 2024-11-21 — — US disclosed
CN-117795096-A Methods, compositions and kits for preparing sequencing libraries 吉复生物科技有限公司 2024-03-29 — — CN disclosed
WO-2022263807-A1 METHODS, COMPOSITIONS, AND KITS FOR PREPARING SEQUENCING LIBRARY GENEFIRST LIMITED (GB) 2022-12-22 — — WO disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 — — EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 — — US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 — — US disclosed
US-10584363-B2 Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same TAKARA BIO USA, INC. (US) 2020-03-10 — — US disclosed
US-20180100181-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-12 — — US disclosed
EP-3283638-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2018-02-21 — — EP disclosed
US-20170349927-A1 METHODS OF PRODUCING AND USING SINGLE-STRANDED DEOXYRIBONUCLEIC ACIDS AND COMPOSITIONS FOR USE IN PRACTICING THE SAME TAKARA BIO USA, INC. 2017-12-07 — — US disclosed
WO-2016168711-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-10-20 — — WO disclosed
US-5721350-A Deuterated nucleosides CHATTOPADHYAYA JYOTI (SE) 1998-02-24 — — US disclosed
WO-1993025566-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA JYOTI (SE) 1993-12-23 — — WO disclosed
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