Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996875 | 0.78 | CNR2 (0.31) | MEN1KMT2ATDP1CNR2CDK4 | |
| SCHEMBL3076232 | 0.71 | ACACB (0.32) | BACE1GRM1 | |
| SCHEMBL12238052 | 0.71 | ACACB (0.31) | — | |
| SCHEMBL13070822 | 0.70 | ACACB (0.48) | BACE1GRM1CDK4CCND1GSK3B | |
| SCHEMBL2888125 | 0.70 | ACACB (0.34) | KMT2ABACE1GRM1 | |
| SCHEMBL2886584 | 0.69 | ACACB (0.33) | KMT2ABACE1 | |
| SCHEMBL3001186 | 0.68 | KMT2A (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5435809 | 0.67 | BACE1 (0.32) | BACE1 | |
| SCHEMBL13071070 | 0.67 | ACACB (0.38) | — | |
| SCHEMBL13070820 | 0.66 | ACACB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718186-B2 | 2-alkoxy-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20080220973-A1 | 2-Alkoxy-6-Alkyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220973-A1 | 2-Alkoxy-6-Alkyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | DDT, PAOX, PTPRG | MEN1 4769/4885KMT2A 1494/4885TDP1 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.