Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076232 | 0.92 | ACACB (0.32) | ACACBACACA | |
| SCHEMBL2886584 | 0.89 | ACACB (0.33) | ACACBACACAKMT2A | |
| SCHEMBL3001186 | 0.88 | KMT2A (0.36) | MEN1KMT2A | |
| SCHEMBL5435809 | 0.87 | BACE1 (0.32) | ACACBACACA | |
| SCHEMBL5429034 | 0.82 | DPP4 (0.37) | ACACBACACA | |
| SCHEMBL5432156 | 0.82 | BACE1 (0.36) | — | |
| SCHEMBL3077698 | 0.79 | THRB (0.37) | MEN1KMT2A | |
| SCHEMBL13360439 | 0.78 | MEN1 (0.32) | CNR2MEN1KMT2ATDP1CDK4 | |
| SCHEMBL2889210 | 0.73 | KMT2A (0.41) | KMT2A | |
| SCHEMBL16562503 | 0.73 | ACACB (0.32) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253207-A1 | Substituted phenyl acetic acid esters | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2216316-A1 | Phenyl acetic acid derivatives | Bayer CropScience Aktiengesellschaft (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-2216317-A1 | Phenyl acetic acid halogenides | Bayer CropScience AG (DE) | 2010-08-11 | — | — | EP | disclosed |
| US-20100174084-A1 | 2-Alkoxy-6-alkyl-phenyl-substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
| US-7718186-B2 | 2-alkoxy-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20080220973-A1 | 2-Alkoxy-6-Alkyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1809634-A1 | 2-ALKOXY-6-ALKYL-PHENYL-SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006056281-A1 | 2-ALKOXY-6-ALKYL-PHENYL-SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220973-A1 | 2-Alkoxy-6-Alkyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | DDT, PAOX, PTPRG | CNR2 2800/4885ACACB 509/4885ACACA 617/4885 |
| US-20100174084-A1 | 2-Alkoxy-6-alkyl-phenyl-substituted Spirocyclic Tetramic Acid Derivatives | DDT, PAOX, PTPRG | CNR2 2800/4885ACACB 509/4885ACACA 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.