Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | ACACA | Q13085 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076232 | 0.94 | ACACB (0.32) | ACACBACACADPP4BACE1CHRM2 | |
| SCHEMBL5435809 | 0.89 | BACE1 (0.32) | ACACBACACABACE1 | |
| SCHEMBL2996875 | 0.89 | CNR2 (0.31) | ACACBACACAKMT2A | |
| SCHEMBL2889210 | 0.84 | KMT2A (0.41) | KMT2A | |
| SCHEMBL5432156 | 0.84 | BACE1 (0.36) | BACE1 | |
| SCHEMBL5429034 | 0.84 | DPP4 (0.37) | ACACBACACADPP4BACE1 | |
| SCHEMBL3077698 | 0.81 | THRB (0.37) | KMT2A | |
| SCHEMBL2888125 | 0.78 | ACACB (0.34) | ACACBACACADPP4BACE1KMT2A | |
| SCHEMBL1344157 | 0.78 | ACACB (0.39) | ACACBACACADPP4BACE1 | |
| SCHEMBL9410107 | 0.78 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727933-B2 | 2-ethyl-4,6-dimethyl-phenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20070298969-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFF (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1687272-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049569-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298969-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | DDT, PKD2, CYP2D6 | ACACB 1784/4885ACACA 1730/4885DPP4 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.