Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076232 | 0.92 | ACACB (0.32) | BACE1ACACBACACA | |
| SCHEMBL2886584 | 0.89 | ACACB (0.33) | BACE1ACACBACACA | |
| SCHEMBL2996875 | 0.87 | CNR2 (0.31) | ACACBACACA | |
| SCHEMBL5432156 | 0.86 | BACE1 (0.36) | BACE1APP | |
| SCHEMBL5437164 | 0.85 | KMT2A (0.38) | — | |
| SCHEMBL5429034 | 0.82 | DPP4 (0.37) | BACE1ACACBACACA | |
| SCHEMBL3077698 | 0.79 | THRB (0.37) | — | |
| SCHEMBL1943774 | 0.77 | BACE1 (0.37) | BACE1ACACBACACA | |
| SCHEMBL2072081 | 0.77 | BACE1 (0.37) | BACE1ACACBACACA | |
| SCHEMBL5458693 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1697321-A1 | 2-HALOGEN-6-ALKYL-PHENYL SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005044796-A1 | 2-HALOGEN-6-ALKYL-PHENYL SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | TBCA, CA6, TRIP13 | BACE1 4650/4885APP 4377/4885ACACB 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.