Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328248 | 0.87 | PIK3CD (0.39) | PIK3CDDPP4DPP8DPP9SMN1; SMN2 | |
| SCHEMBL13360294 | 0.85 | CHRNB2 (0.43) | PIK3CDDPP4DPP8DPP9ATM | |
| SCHEMBL22099648 | 0.82 | MEN1 (0.40) | PIK3CDATM | |
| SCHEMBL22946712 | 0.81 | CHRNB2 (0.40) | PIK3CDDPP4DPP8DPP9ATM | |
| SCHEMBL24012411 | 0.80 | SMN1; SMN2 (0.49) | PIK3CDDPP4DPP8DPP9SMN1; SMN2 | |
| SCHEMBL20980408 | 0.79 | CHRNB2 (0.39) | PIK3CDDPP4DPP8DPP9SMN1; SMN2 | |
| SCHEMBL18750448 | 0.79 | L3MBTL1 (0.41) | — | |
| SCHEMBL19710591 | 0.78 | PIK3CD (0.59) | PIK3CDDPP4DPP8DPP9ATM | |
| SCHEMBL13032621 | 0.77 | MEN1 (0.41) | — | |
| SCHEMBL2933741 | 0.75 | ATM (0.44) | PIK3CDDPP4DPP8DPP9ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236755-A2 | ANGIOTENSIN II TYPE 1 RECEPTOR TARGETED OLIGONUCLEOTIDES AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2020-11-26 | — | — | WO | disclosed |
| US-7713944-B2 | Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |