Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.76 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.50 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5614193 | 1.00 | PTPN1 (1.00) | PTPN1HSP90AA1GABRA1GABRB2ACHE | |
| SCHEMBL30288230 | 0.90 | PTPN1 (0.81) | PTPN1HSP90AA1GABRA1GABRB2ACHE | |
| SCHEMBL26112000 | 0.89 | PTPN1 (0.81) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL30631321 | 0.89 | PTPN1 (0.81) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL30523853 | 0.89 | PTPN1 (0.81) | PTPN1HSP90AA1GABRA1GABRB2TYR | |
| SCHEMBL27013629 | 0.86 | HSP90AA1 (1.00) | PTPN1HSP90AA1GABRA1GABRB2ACHE | |
| SCHEMBL30266617 | 0.86 | HSP90AA1 (1.00) | PTPN1HSP90AA1GABRA1GABRB2ACHE | |
| Licorisoflavan A SCHEMBL29907989 | 0.85 | PTPN1 (0.88) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL13360710 | 0.85 | PTPN1 (0.74) | PTPN1HSP90AA1GABRA1GABRB2ACHE | |
| SCHEMBL31290568 | 0.84 | PTPN1 (0.72) | PTPN1HSP90AA1ACHETYRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12102653-B2 | Ligand regulated protein-protein interaction system | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2024-10-01 | — | — | US | disclosed |
| US-20240000841-A1 | LIGAND REGULATED PROTEIN-PROTEIN INTERACTION SYSTEM | ST ANNA KINDERKREBSFORSCHUNG (AT) | 2024-01-04 | — | — | US | disclosed |
| US-11844813-B2 | Ligand regulated protein-protein interaction system | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2023-12-19 | — | — | US | disclosed |
| US-20220041687-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2022-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041687-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | CARS1, CD74, HAVCR2 | PTPN1 1563/4885HSP90AA1 1177/4885GABRA1 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.