Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD2 | P13995 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PRLHR | P49683 | 6/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328897 | 0.89 | CCR5 (0.44) | MTHFD2PDE10APRLHRCCR5 | |
| SCHEMBL13328898 | 0.88 | TSHR (0.45) | MTHFD2LMNAKMT2ACCR5 | |
| SCHEMBL13328913 | 0.87 | MGLL (0.47) | MTHFD2LMNAPDE10APRLHR | |
| SCHEMBL13328838 | 0.87 | MTHFD2 (0.42) | MTHFD2LMNAPDE10APRLHRCCR5 | |
| SCHEMBL13328836 | 0.86 | MAPT (0.43) | MTHFD2PDE10A | |
| SCHEMBL13328906 | 0.85 | PPARG (0.42) | MTHFD2PDE10ACCR5 | |
| SCHEMBL13328919 | 0.85 | KDR (0.47) | — | |
| SCHEMBL13328918 | 0.85 | MGLL (0.42) | MTHFD2PDE10APRLHR | |
| SCHEMBL13328901 | 0.85 | PPARG (0.41) | MTHFD2LMNACCR5 | |
| SCHEMBL13329561 | 0.84 | KMT2A (0.42) | MTHFD2KMT2ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130584-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |