Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.41 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621834 | 0.89 | ALDH1A1 (0.55) | ALDH1A1OPRM1BLMCHRNB2CHRNA3 | |
| SCHEMBL14277668 | 0.84 | ALDH1A1 (0.50) | ALDH1A1OPRM1BLMCHRNB2CHRNA3 | |
| SCHEMBL13804168 | 0.83 | ALDH1A1 (0.48) | ALDH1A1OPRM1BLMCHRNB2CHRNA3 | |
| SCHEMBL16887630 | 0.83 | ALDH1A1 (0.48) | ALDH1A1OPRM1BLMCHRNB2CHRNA3 | |
| SCHEMBL327615 | 0.82 | ALDH1A1 (0.47) | ALDH1A1OPRM1BLMCHRNB2CHRNA3 | |
| SCHEMBL15998851 | 0.82 | ALDH1A1 (0.47) | ALDH1A1OPRM1BLMCHRNB2CHRNA3 | |
| SCHEMBL14417828 | 0.82 | NAMPT (0.42) | ALDH1A1EPHX2NAMPTMEN1TSHR | |
| SCHEMBL8903167 | 0.80 | NAMPT (0.37) | ALDH1A1OPRM1EPHX2NAMPTMEN1 | |
| SCHEMBL10074073 | 0.80 | ALDH1A1 (0.45) | ALDH1A1OPRM1BLMCHRNB2CHRNA3 | |
| SCHEMBL4438715 | 0.80 | ALDH1A1 (0.53) | ALDH1A1NAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382906-A1 | NOVEL JAK INHIBITOR COMPOUNDS, METHODS FOR SYNTHESIZING SAME AND USE THEREOF | Galderma Holding SA (CH) | 2023-11-30 | — | — | US | disclosed |
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382906-A1 | NOVEL JAK INHIBITOR COMPOUNDS, METHODS FOR SYNTHESIZING SAME AND USE THEREOF | JAK1, JAK2, JAK3 | ALDH1A1 2193/4885OPRM1 4395/4885BLM 3595/4885 |
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | CNR1, CNR2, OPRL1 | ALDH1A1 1706/4885OPRM1 4/4885BLM 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.