Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13360768 | 0.80 | ALDH1A1 (0.52) | NAMPTALDH1A1EPHX2L3MBTL1MEN1 | |
| SCHEMBL14417828 | 0.80 | NAMPT (0.42) | NAMPTALDH1A1EPHX2L3MBTL1ATM | |
| SCHEMBL13438125 | 0.78 | CPN1 (0.39) | NAMPTALDH1A1EPHX2ATMKDM4E | |
| SCHEMBL14417834 | 0.78 | NAMPT (0.37) | NAMPTALDH1A1EPHX2L3MBTL1ATM | |
| SCHEMBL13194913 | 0.78 | ALDH1A1 (0.41) | NAMPTALDH1A1EPHX2L3MBTL1ATM | |
| SCHEMBL4438715 | 0.78 | ALDH1A1 (0.53) | NAMPTALDH1A1LMNASPR | |
| SCHEMBL9275712 | 0.78 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1ATMKDM4EMEN1 | |
| SCHEMBL8903212 | 0.78 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1ATMKDM4EMEN1 | |
| SCHEMBL13194846 | 0.78 | OPRM1 (0.35) | NAMPTALDH1A1OPRM1 | |
| SCHEMBL8904836 | 0.77 | ALDH1A1 (0.41) | ALDH1A1ATMUSP2CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0648213-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |