Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16181356 | 0.85 | KMT2A (0.59) | KMT2AHSD17B10MAPK1MEN1LMNA | |
| SCHEMBL31466159 | 0.83 | KMT2A (0.57) | KMT2AHSD17B10MAPK1MEN1LMNA | |
| SCHEMBL226481 | 0.81 | KMT2A (0.54) | KMT2AHSD17B10MAPK1MEN1LMNA | |
| SCHEMBL8904582 | 0.81 | KMT2A (0.51) | KMT2AHSD17B10MAPK1MEN1LMNA | |
| SCHEMBL21480181 | 0.81 | OPRM1 (0.41) | KMT2AHSD17B10MAPK1MEN1LMNA | |
| SCHEMBL6338363 | 0.80 | L3MBTL1 (0.57) | KMT2AHSD17B10MEN1LMNASMN1; SMN2 | |
| SCHEMBL13088273 | 0.79 | KMT2A (0.56) | KMT2AHSD17B10MAPK1MEN1LMNA | |
| SCHEMBL14542492 | 0.79 | ALDH1A1 (0.52) | KMT2AHSD17B10MAPK1MEN1LMNA | |
| SCHEMBL12526186 | 0.78 | OPRM1 (0.42) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL14467628 | 0.78 | ALDH1A1 (0.58) | KMT2AHSD17B10MAPK1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | CNR1, CNR2, OPRL1 | KMT2A 2274/4885HSD17B10 3639/4885MAPK1 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.