Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 12/20 | 0.51 |
| ▸ | CTSS | P25774 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805173 | 1.00 | PPARA (0.53) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL17393 | 1.00 | PPARA (0.53) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL31407501 | 0.96 | PPARA (0.52) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL24633954 | 0.91 | PPARA (0.55) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL21837472 | 0.91 | PPARA (0.55) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL21837471 | 0.91 | PPARA (0.55) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL7761525 | 0.90 | PPARA (0.47) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL14174566 | 0.87 | PPARA (0.43) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL15243753 | 0.87 | CTSK (0.53) | PPARACTSKCTSSPPARGITGB3 | |
| SCHEMBL20057099 | 0.87 | CTSK (0.49) | PPARACTSKCTSSPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222430-A1 | D-ALA-D-ALA-BASED DIPEPTIDES AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2016-08-04 | — | — | US | disclosed |
| US-9394297-B2 | Amides as pim inhibitors | AMGEN INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150329538-A1 | AMIDES AS PIM INHIBITORS | AMGEN INC. (US) | 2015-11-19 | — | — | US | disclosed |
| WO-2015038764-A1 | D-ALA-D-ALA-BASED DIPEPTIDES AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2010054102-A2 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329538-A1 | AMIDES AS PIM INHIBITORS | PIM1, PIM3, PIM2 | PPARA 1196/4885CTSK 2770/4885CTSS 3374/4885 |
| US-20160222430-A1 | D-ALA-D-ALA-BASED DIPEPTIDES AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | DNPEP, DDOST, ALAD | PPARA 1274/4885CTSK 2038/4885CTSS 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.