Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.45 |
| ▸ | CTSK | P43235 | 7/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407501 | 0.94 | PPARA (0.52) | PPARAPPARGPLA2G2CCTSKCTSS | |
| SCHEMBL17393 | 0.90 | PPARA (0.53) | PPARAPPARGCTSKCTSSITGB3 | |
| SCHEMBL13365298 | 0.90 | PPARA (0.53) | PPARAPPARGCTSKCTSSITGB3 | |
| SCHEMBL805173 | 0.90 | PPARA (0.53) | PPARAPPARGCTSKCTSSITGB3 | |
| SCHEMBL24633954 | 0.84 | PPARA (0.55) | PPARAPPARGCTSKCTSSITGB3 | |
| SCHEMBL21837471 | 0.84 | PPARA (0.55) | PPARAPPARGCTSKCTSSITGB3 | |
| SCHEMBL21837472 | 0.84 | PPARA (0.55) | PPARAPPARGCTSKCTSSITGB3 | |
| SCHEMBL28854983 | 0.82 | CTSK (0.46) | PLA2G2CCTSKCTSSBCHEACHE | |
| SCHEMBL5139651 | 0.82 | CTSK (0.55) | PPARACTSKCTSSITGAVITGB6 | |
| SCHEMBL5139652 | 0.82 | CTSK (0.55) | PPARACTSKCTSSITGAVITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251882-B1 | TREATING LEUKEMIA, BREAST CANCER, PROSTATE CANCER, OR BRAIN TUMOR | PARKER HUGHES INSTITUTE | 2001-06-26 | — | — | US | claimed |
| EP-1091934-A2 | ALKYL KETONES AS POTENT ANTI-CANCER AGENTS | Parker Hughes Institute (US) | 2001-04-18 | — | — | EP | claimed |
| WO-2000000469-A2 | ALKYL KETONES AS POTENT ANTI-CANCER AGENTS | PARKER HUGHES INSTITUTE (US) | 2000-01-06 | — | — | WO | claimed |
| US-6251882-B1 | TREATING LEUKEMIA, BREAST CANCER, PROSTATE CANCER, OR BRAIN TUMOR | PARKER HUGHES INSTITUTE | 2001-06-26 | — | — | US | disclosed |
| EP-1091934-A2 | ALKYL KETONES AS POTENT ANTI-CANCER AGENTS | Parker Hughes Institute (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000469-A2 | ALKYL KETONES AS POTENT ANTI-CANCER AGENTS | PARKER HUGHES INSTITUTE (US) | 2000-01-06 | — | — | WO | disclosed |