Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087061 | 0.80 | GAA (0.73) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL2286641 | 0.79 | GAA (0.66) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL13655633 | 0.77 | GAA (0.54) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL7610019 | 0.76 | CYP2D6 (0.61) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL622501 | 0.76 | GAA (0.68) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL392625 | 0.76 | ALDH1A1 (0.82) | GAAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL1186049 | 0.76 | GAA (0.68) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL414454 | 0.76 | GAA (0.68) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL3074777 | 0.76 | GAA (0.61) | GAAKMT2AMEN1MCL1ALDH1A1 | |
| SCHEMBL16714720 | 0.75 | GAA (0.66) | GAAKMT2AMEN1MCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871916-B2 | Diaryl phosphine compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-8350014-B2 | Preparation of diazo and diazonium compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | TREH, TALDO1, LIPE | GAA 319/4885KMT2A 1865/4885MEN1 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.