Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 3/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14023373 | 0.90 | CNR1 (0.41) | CNR1CNR2GRIN1GRIN2BSLC2A1 | |
| SCHEMBL3112624 | 0.85 | ALDH1A1 (0.48) | CNR1CNR2GRIN1GRIN2BNPBWR1 | |
| SCHEMBL3117441 | 0.82 | ALDH1A1 (0.48) | CNR1CNR2GRIN1GRIN2BNPBWR1 | |
| SCHEMBL14023375 | 0.78 | ADORA2A (0.40) | ALDH1A1KDM4EMAPTGLAGAA | |
| SCHEMBL14023412 | 0.78 | KDM4E (0.39) | CNR2ALDH1A1KDM4EMAPTGLA | |
| SCHEMBL21608784 | 0.77 | NPBWR1 (0.45) | CNR1CNR2GRIN1GRIN2BSLC2A1 | |
| SCHEMBL3289718 | 0.77 | CNR1 (0.50) | CNR1CNR2GRIN1GRIN2BSLC2A1 | |
| SCHEMBL12315708 | 0.75 | CNR2 (0.49) | CNR1CNR2GRIN1GRIN2BNPBWR1 | |
| SCHEMBL25380409 | 0.71 | CNR1 (0.46) | CNR1CNR2GRIN1GRIN2BSLC2A1 | |
| SCHEMBL21608367 | 0.71 | NPBWR1 (0.47) | CNR1CNR2SLC2A1NPBWR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010055304-A2 | PHARMACEUTICAL COMPOUNDS | SAREUM LIMITED (GB) | 2010-05-20 | — | — | WO | disclosed |
| WO-2008139161-A1 | OXAZOLE TYROSINE KINASE INHIBITORS | SAREUM LIMITED (GB) | 2008-11-20 | — | — | WO | disclosed |