Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 7/20 | 0.47 |
| ▸ | PDE1A | P54750 | 5/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21608784 | 0.86 | NPBWR1 (0.45) | NPBWR1PDE1APDE1BPDE1CPKM | |
| SCHEMBL3289718 | 0.80 | CNR1 (0.50) | NPBWR1PDE1APDE1BPDE1CPKM | |
| SCHEMBL25380409 | 0.79 | CNR1 (0.46) | NPBWR1PDE1APDE1BPDE1CPKM | |
| SCHEMBL1491119 | 0.77 | TSHR (0.67) | NPBWR1PDE1APDE1BPDE1CMEN1 | |
| SCHEMBL12315708 | 0.76 | CNR2 (0.49) | NPBWR1PDE1APDE1BPDE1CPKM | |
| SCHEMBL15182487 | 0.76 | DRD2 (0.44) | NPBWR1PDE1APDE1BPDE1CPKM | |
| SCHEMBL4679664 | 0.76 | NPBWR1 (0.61) | NPBWR1PDE1APDE1BPDE1CPKM | |
| SCHEMBL21579426 | 0.75 | ALDH1A1 (0.47) | NPBWR1PDE1APDE1BPDE1CPKM | |
| SCHEMBL20401464 | 0.75 | QPCT (0.48) | NPBWR1PDE1APDE1BPDE1CMCHR1 | |
| SCHEMBL29447767 | 0.75 | QPCT (0.48) | NPBWR1PDE1APDE1BPDE1CMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277003-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-09 | — | — | US | disclosed |
| WO-2019243535-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277003-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | NPBWR1 4748/4885PDE1A 3760/4885PDE1B 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.