SCHEMBL13367145

SCHEMBL13367145

CC(C)(C)CC(c1ccc(CN)cc1)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.38
LOXL2 Q9Y4K0 5/20 0.37
ABAT P80404 1/20 0.35
ST14 Q9Y5Y6 1/20 0.35
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
IDO1 P14902 2/20 0.33
PSIP1 O75475 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
SLC6A4 P31645 1/20 0.33
MAOB P27338 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14540206 1.00 HRH3 (0.38) HRH3LOXL2ABATST14NOS3
SCHEMBL23352958 0.87 HRH3 (0.37) HRH3LOXL2ABATST14NOS3
SCHEMBL24858431 0.84 HRH3 (0.34) HRH3LOXL2ABATST14NOS3
SCHEMBL13752316 0.81 PPARG (0.40) NOS3NOS1
SCHEMBL29293451 0.81 ESR1 (0.31)
SCHEMBL23034842 0.81 ESR1 (0.31)
SCHEMBL13958028 0.81 TAAR1 (0.42) HRH3LOXL2ABATNOS3NOS1
SCHEMBL13702479 0.80 ALDH1A1 (0.35) LOXL2IDO1
SCHEMBL21935009 0.79 LPL (0.37)
SCHEMBL507696 0.78 HRH3 (0.39) HRH3LOXL2ABATNOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124829-B2 Flow cells ILLUMINA, INC. (US) 2021-09-21 US disclosed
EP-3677435-A1 PRINTING PLATE AND PRINTING PLATE LAMINATE BODY FUJIFILM Corporation (JP) 2020-07-08 EP disclosed
WO-2017168419-A1 ANTIMICROBIAL POLYMERIC PARTICLES BAR-ILAN RESEARCH & DEVELOPMENT COMPANY LTD (IL) 2017-10-05 WO disclosed
EP-2184642-A2 Lithographic printing plate precursor and method of preparing lithographic printing plate FUJIFILM Corporation (JP) 2010-05-12 EP disclosed
EP-1834802-B1 Infrared-sensitive lithographic printing plate FUJIFILM CORP (JP) 2009-01-14 EP disclosed
EP-1752308-B1 Lithographic printing plate support, method of manufacturing the same, and presensitized plate FUJIFILM CORP (JP) 2008-05-07 EP disclosed
EP-1251014-B1 Support for lithographic printing plate and presensitized plate FUJIFILM CORP (JP) 2007-07-11 EP disclosed
EP-1270258-B1 SUPPORTING BODY FOR LITHOGRAPHY BLOCK AND ORIGINAL LITHOGRAPHY BLOCK FUJIFILM CORP (JP) 2007-04-04 EP disclosed