Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613744 | 0.87 | THRA (0.38) | CNR2TP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL15613740 | 0.86 | TSHR (0.53) | TP53TSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16644656 | 0.82 | RARB (0.42) | CNR2TP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL12697313 | 0.79 | TSHR (0.51) | CNR2TP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL15959660 | 0.79 | NOTUM (0.53) | TSHRKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2240565 | 0.78 | HPGD (0.44) | NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14829178 | 0.78 | MAPT (0.46) | TP53KDM4EALDH1A1TDP1 | |
| SCHEMBL13367279 | 0.77 | CNR2 (0.39) | CNR2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL17980842 | 0.76 | TSHR (0.53) | TP53TSHRPLA2G4BPTPN11KDM4E | |
| Hydrazine SCHEMBL3431213 | 0.75 | MAPT (0.44) | TP53KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439984-B2 | Macrocycles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150157746-A1 | MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-11 | — | — | US | disclosed |
| WO-2013187971-A2 | MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-19 | — | — | WO | disclosed |
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |
| WO-2007121453-A2 | 2-HYDROXY-1-OXO 1,2 DIHYDRO ISOQUINOLINE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150157746-A1 | MACROCYCLES | SLC39A14, SLC39A3, SLC40A1 | CNR2 3216/4885TP53 890/4885TSHR 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.