Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13367284 | 0.86 | KDM4E (0.41) | CNR2LIPGLIPCALDH1A1TSHR | |
| SCHEMBL8333545 | 0.84 | LIPG (0.43) | LIPGLIPCALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16350307 | 0.82 | LIPG (0.37) | CNR2LIPGLIPCALDH1A1TSHR | |
| SCHEMBL14402636 | 0.81 | ALOX5 (0.39) | CNR2LIPGLIPCALDH1A1TSHR | |
| SCHEMBL13367288 | 0.77 | CNR2 (0.43) | CNR2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13339884 | 0.76 | SPHK2 (0.48) | LIPGLIPCALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15613744 | 0.76 | THRA (0.38) | CNR2LIPGALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8335413 | 0.75 | BRD4 (0.48) | LIPGLIPCALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15613740 | 0.74 | TSHR (0.53) | ALDH1A1TSHRMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL15119487 | 0.74 | CNR2 (0.40) | CNR2LIPGLIPCALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |