SCHEMBL13367444

SCHEMBL13367444

CN(c1ccc2ccccc2c1)c1nccc2ccccc12

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.43
CYP2A6 P11509 1/20 0.43
CNR2 P34972 2/20 0.43
EGFR P00533 4/20 0.40
PDGFRB P09619 3/20 0.40
KDR P35968 3/20 0.40
F12 P00748 1/20 0.40
PLAU P00749 1/20 0.40
NCF1 P14598 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
BACE1 P56817 1/20 0.40
KDM4E B2RXH2 1/20 0.39
DOT1L Q8TEK3 1/20 0.38
PDE5A O76074 2/20 0.38
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13367359 0.83 EGFR (0.56) S100A4CYP2A6CNR2EGFRF12
SCHEMBL13367553 0.83 CYP2A6 (0.55) S100A4CYP2A6CNR2EGFRF12
SCHEMBL31098990 0.83 CYP2A6 (0.49) S100A4CYP2A6CNR2EGFRPDGFRB
SCHEMBL13367560 0.83 CYP2A6 (0.49) S100A4CYP2A6CNR2EGFRPDGFRB
SCHEMBL3113118 0.82 EGFR (0.57) EGFRPDGFRBKDR
SCHEMBL13367465 0.82 CSF1R (0.53) CYP2A6EGFR
SCHEMBL13367577 0.81 CYP2A6 (0.47) S100A4CYP2A6CNR2EGFRF12
SCHEMBL13367494 0.81 PDE5A (0.48) S100A4CYP2A6CNR2EGFRKDM4E
SCHEMBL31098986 0.81 S100A4 (0.43) S100A4CYP2A6CNR2EGFRF12
SCHEMBL13338449 0.81 KDM4E (0.41) S100A4CYP2A6CNR2EGFRPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 S100A4 2341/4885CYP2A6 2286/4885CNR2 1320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.