Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13367359 | 0.90 | EGFR (0.56) | PDE5AEGFRS100A4CYP2A6CNR2 | |
| SCHEMBL31098990 | 0.86 | CYP2A6 (0.49) | EGFRS100A4CYP2A6CNR2KDM4E | |
| SCHEMBL13367560 | 0.86 | CYP2A6 (0.49) | EGFRS100A4CYP2A6CNR2KDM4E | |
| SCHEMBL31098986 | 0.84 | S100A4 (0.43) | PDE5AEGFRS100A4CYP2A6ABCG2 | |
| SCHEMBL13367553 | 0.83 | CYP2A6 (0.55) | EGFRS100A4CYP2A6CNR2KDM4E | |
| SCHEMBL3113118 | 0.82 | EGFR (0.57) | EGFR | |
| SCHEMBL13367444 | 0.81 | S100A4 (0.43) | PDE5AEGFRS100A4CYP2A6CNR2 | |
| SCHEMBL13338707 | 0.81 | LMNA (0.40) | S100A4CYP2A6CNR2KCNH2KDM4E | |
| SCHEMBL13367577 | 0.78 | CYP2A6 (0.47) | EGFRS100A4CYP2A6CNR2KMT2A | |
| SCHEMBL13231255 | 0.78 | KCNH2 (0.39) | PDE5AS100A4CYP2A6CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100108997-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100108997-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | OR10J3, OCIAD1, OCIAD2 | PDE5A 4323/4885EGFR 1659/4885S100A4 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.