SCHEMBL13367476

SCHEMBL13367476

Cc1cccc(N(C)c2cccnc2)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.44
GRM5 P41594 4/20 0.44
CLK1 P49759 1/20 0.44
CLK2 P49760 1/20 0.44
DYRK1A Q13627 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
CSF1R P07333 4/20 0.43
EGFR P00533 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP2A6 P11509 1/20 0.41
NPY5R Q15761 1/20 0.41
TSHR P16473 2/20 0.40
KCNA5 P22460 1/20 0.40
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13367575 0.87 KCNA5 (0.41) GRM5SMN1; SMN2KDM4EALDH1A1CYP2A6
SCHEMBL3409401 0.84 KCNA5 (0.49) GRM5ALDH1A1CYP2A6KCNA5
Hydrochloric Acid SCHEMBL4024971 0.82 KCNA5 (0.47) GRM5ALDH1A1CYP2A6KCNA5
SCHEMBL1697445 0.82 ACHE (0.55) CSF1REGFRSMN1; SMN2ALDH1A1TSHR
SCHEMBL12947815 0.81 RAB9A (0.45) KDM4CGRM5ALDH1A1CYP2A6TSHR
SCHEMBL13367477 0.81 KDM4C (0.46) KDM4CCLK1CLK2DYRK1ACLK4
SCHEMBL12412921 0.81 MEN1 (0.51) GRM5EGFRKCNA5
SCHEMBL6732495 0.81 ALDH1A1 (0.53) GRM5KDM4EALDH1A1TSHRKCNA5
SCHEMBL23079716 0.79 CYP19A1 (0.45) GRM5CLK4ALDH1A1CYP2A6TSHR
SCHEMBL5075470 0.79 KCNA5 (0.50) GRM5ALDH1A1CYP2A6KCNA5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 KDM4C 3304/4885GRM5 1277/4885CLK1 3170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.