Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376720 | 0.86 | F2 (0.57) | F2ALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL13911894 | 0.80 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL2565715 | 0.78 | F2 (0.51) | F2ALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL2565712 | 0.76 | F2 (0.50) | F2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL12231007 | 0.75 | TDP1 (0.62) | F2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL12192278 | 0.74 | HDAC1 (0.49) | F2ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL13306912 | 0.74 | KMT2A (0.47) | F2ALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL8526512 | 0.74 | RAB9A (0.87) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL799431 | 0.74 | RAB9A (0.87) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8507346 | 0.74 | RAB9A (0.87) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723330-B2 | Heterobicyclic pyrazole compounds and methods of use | ARRAY BIOPHARMA INC. (US) | 2010-05-25 | — | — | US | disclosed |