Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.58 |
| ▸ | HRH1 | P35367 | 12/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368695 | 0.88 | HTR6 (0.67) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL13368694 | 0.85 | HTR6 (0.55) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL2362746 | 0.84 | HTR6 (0.63) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL2361460 | 0.83 | HTR6 (0.52) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL13368745 | 0.82 | HTR6 (0.58) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL10127795 | 0.81 | HTR6 (0.59) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL2362577 | 0.81 | HTR6 (0.50) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL2362640 | 0.81 | HTR6 (0.56) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL13368701 | 0.80 | HTR6 (0.54) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL13241776 | 0.79 | HTR6 (0.65) | HTR6HRH1ADRA2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120792-A1 | Substituted 2,3,4,5-Tetrahyrdo-1H-Pyrido[4,3-B]Indoles, Methods for the Production and Use Thereof | ALLA CHEM, LLC | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120792-A1 | Substituted 2,3,4,5-Tetrahyrdo-1H-Pyrido[4,3-B]Indoles, Methods for the Production and Use Thereof | HTR3C, HTR3A, HTR6 | HTR6 3/4885HRH1 75/4885ADRA2A 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.