SCHEMBL13369020

SCHEMBL13369020

NCc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.75
▸ L3MBTL1 Q9Y468 1/20 0.75
▸ MEN1 O00255 2/20 0.63
▸ POLB P06746 2/20 0.63
▸ KMT2A Q03164 2/20 0.63
▸ ALPL P05186 1/20 0.63
▸ ALPI P09923 1/20 0.63
▸ ALPG P10696 1/20 0.63
▸ CA9 Q16790 15/20 0.59
▸ CA1 P00915 13/20 0.59
▸ CA2 P00918 13/20 0.59
▸ CA12 O43570 5/20 0.59
▸ CA14 Q9ULX7 3/20 0.59
▸ ATM Q13315 1/20 0.58
▸ PLEC Q15149 1/20 0.58
▸ CA7 P43166 3/20 0.57
▸ ESR1 P03372 1/20 0.55
▸ DNASE1L3 Q13609 1/20 0.54
▸ PRMT1 Q99873 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060092 0.89 USP2 (0.72) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14619875 0.89 USP2 (0.72) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20056705 0.88 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL29668458 0.87 USP2 (0.68) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL18383481 0.87 USP2 (0.68) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3481432 0.86 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL30023431 0.86 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL23318855 0.85 USP2 (0.66) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL1437042 0.84 USP2 (0.78) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20254033 0.84 USP2 (0.77) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100112619-A1 LIGAND-CONTAINING MICELLES AND USES THEREOF GRAHAM RONALD J 2010-05-06 — — US disclosed
US-20090047699-A1 FLUOROGENIC ENZYME ACTIVITY ASSAY METHODS AND COMPOSITIONS USING FRAGMENTABLE LINKERS APPLIED BIOSYSTEMS INC. (US) 2009-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090047699-A1 FLUOROGENIC ENZYME ACTIVITY ASSAY METHODS AND COMPOSITIONS USING FRAGMENTABLE LINKERS BCHE, SI, ENGASE USP2 493/4885L3MBTL1 3397/4885MEN1 1170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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