Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28096623 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL27789588 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL28203642 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL27832156 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL27449009 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL4721637 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL27766871 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL28096081 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL29354528 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM | |
| Quinoline SCHEMBL27851343 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTCASP1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341389-B | Nitrogen-containing aromatic heterocycle substituted quinoline formamide derivative and application thereof | 浙江工业大学 | 2022-07-29 | — | — | CN | claimed |
| CN-112341389-A | Nitrogen-containing aromatic heterocycle substituted quinoline formamide derivative and application thereof | 浙江工业大学 | 2021-02-09 | — | — | CN | claimed |
| CN-110590660-A | Quinoline carboxamide compound, preparation method thereof and application of quinoline carboxamide compound in resisting enterovirus 71 | 武汉大学 | 2019-12-20 | — | — | CN | claimed |
| CN-108003097-A | A kind of synthetic method of cinchocaine | 山东诚汇双达药业有限公司 | 2018-05-08 | — | — | CN | claimed |
| CN-106177965-A | A kind of containing quinoline or the pharmaceutical composition of its salt | 江苏恒瑞医药股份有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-106139156-A | A kind of pharmaceutical composition containing quinoline or its salt | 江苏恒瑞医药股份有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-104492463-A | TiO2/ AC-SO42-solid acid photocatalyst and application thereof | UNIV NINGXIA | 2015-04-08 | — | — | CN | claimed |
| CN-101481359-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-07-15 | — | — | CN | claimed |
| CN-1348370-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2002-05-08 | — | — | CN | claimed |
| CN-120304428-A | Application and method of quinoline carboxamide compound as prodenia litura insecticidal synergist | 云南省烟草公司文山州公司 | 2025-07-15 | — | — | CN | disclosed |
| CN-118206569-A | Azoline ammonium quinoline carboxamide analogue, pharmaceutical composition, preparation method and medical application thereof | 上海市针灸经络研究所 | 2024-06-18 | — | — | CN | disclosed |
| CN-116082232-A | Monoamine oxidase inhibitor, preparation method and application thereof | 浙江海洋大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-111943957-B | Quinoline formamide compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-01-06 | — | — | CN | disclosed |
| CN-111943957-B | Quinoline formamide compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-01-06 | — | — | CN | disclosed |
| CN-1878765-A | Synthesis of quinoline 5-carboxamides useful for the preparation of PDE IV inhibitors | SCHERING CORP (US) | 2006-12-13 | — | — | CN | disclosed |
| CN-1649885-A | Cellular Accumulation of Phosphonate Analogs of HIV Protease Inhibitor Compounds and Such Compounds | GILEAD SCIENCES INC (US) | 2005-08-03 | — | — | CN | disclosed |
| CN-1476436-A | Novel compounds for use as HIV protease inhibitors | - | 2004-02-18 | — | — | CN | disclosed |
| CN-1128790-C | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents | UPJOHN CO (US) | 2003-11-26 | — | — | CN | disclosed |
| CN-1432001-A | 1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents | UPJOHN CO (US) | 2003-07-23 | — | — | CN | disclosed |
| CN-1281439-A | 4-hydroxyquinoline-3-carboxamide and hydrazide compounds as antiviral agents | UPJOHN CO (US) | 2001-01-24 | — | — | CN | disclosed |