Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL4721637 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL28096081 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL28425004 | 0.98 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL27889103 | 0.98 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL28096623 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL27700047 | 0.89 | ALDH1A1 (0.85) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL27832156 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL27851343 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL27925298 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL28166944 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312713-B2 | Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors | PFIZER INC. (US) | 2022-04-26 | — | — | US | disclosed |
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312713-B2 | Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors | LRRK2, PARK7, BRCA1 | ALDH1A1 1569/4885MEN1 1387/4885KMT2A 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.